{ "nid": "88", "details": "\x3cspan class=\"title\"\x3eNerveWorks™: Historical Hodgkin Huxley\x3c/span\x3e\x3cbr/\x3e\n\x3cspan class=\"description\"\x3eThis is the first of several labs that recreate the famous Hodgkin-Huxley-Katz experiments on squid axons. In this lab you explore how permeability of the cell membrane to ions defines both resting potential and the action potential, within an historical context. In the first part of the lab you study a cell membrane that is selectively permeable to one ion, recording membrane potential, examining ion concentration gradients, calculating Nernst potentials, and predicting resting permeability of the cell membrane. In Part II, you stimulate a model \x26quot;squid axon\x26quot; to fire an action potential, carefully examine the action potential and then repeat experiments done by Hodgkin and Huxley and Katz to show how the action potential works. This is a basic lab and therefore does not assume you know about intracellular recording techniques. \r\n\x3c/span\x3e\x3cbr/\x3e\n\x3cbr/\x3e\n\x3cstrong\x3eKey Concepts\x3c/strong\x3e: Action Potential; Hodgkin-Huxley equations; Membrane potential\x3cbr/\x3e\n\x3cstrong\x3eCourses\x3c/strong\x3e: Neurobiology\x3cbr/\x3e\n          \x3cbr/\x3e\x3ca href=\"/search_result_details/brief/88\" class=\"node_brief\"\x3eRead less\x3c/a\x3e        \x3cbr/\x3e  \x3c/span\x3e \x3c!-- description --\x3e\n" }