{ "nid": "87", "details": "\x3cspan class=\"title\"\x3eNerveWorks™: Ca Dependent K ICa Voltage Clamp\x3c/span\x3e\x3cbr/\x3e\n\x3cspan class=\"description\"\x3eThis is the second lab examining I\x3csub\x3eK (Ca )\x3c/sub\x3e. Here, you use the voltage clamp technique in combination with drugs to isolate and characterize two K currents: calcium-activated K\x3csup\x3e+\x3c/sup\x3e currents (I\x3csub\x3eK(Ca )\x3c/sub\x3e) and voltage-gated I\x3csub\x3eK\x3c/sub\x3e. You prove that these currents are carried by K\x3csup\x3e+\x3c/sup\x3e by predictably shifting the reversal potentials of these currents with changes in the concentration gradient for K\x3csup\x3e+\x3c/sup\x3e.\r\n\x3c/span\x3e\x3cbr/\x3e\n\x3cbr/\x3e\n\x3cstrong\x3eKey Concepts\x3c/strong\x3e: Ca dependent currents\x3cbr/\x3e\n \x3cbr/\x3e\x3ca href=\"/search_result_details/brief/87\" class=\"node_brief\"\x3eRead less\x3c/a\x3e \x3cbr/\x3e \x3c/span\x3e \x3c!-- description --\x3e\n" }