{ "nid": "83", "details": "\x3cspan class=\"title\"\x3eNerveWorks™: Basic Resting Potential\x3c/span\x3e\x3cbr/\x3e\n\x3cspan class=\"description\"\x3eIn this lab you explore the basic factors that determine a cell\'s resting potential. First you record from a cell where only one ion is permeant at rest. You examine the effects of changing the concentration gradient for the permeant ion and use the Nernst equation to predict the effects of these changes on cell resting potential. In Part II, you record from a cell with membrane permeability to two ions and determine that the resting potential must be between the Nernst potentials for these two permeant ions, that total current must be zero and with a mixed membrane permeability to two ions, a 10-x change in the concentration gradient for one of the ions will always produce less that a 59 mV shift in cell membrane potential.\r\n\x3c/span\x3e\x3cbr/\x3e\n\x3cbr/\x3e\n\x3cstrong\x3eKey Concepts\x3c/strong\x3e: Ion channels; Ion charges; Resting potential\x3cbr/\x3e\n\x3cstrong\x3eCourses\x3c/strong\x3e: Neurobiology\x3cbr/\x3e\n \x3cbr/\x3e\x3ca href=\"/search_result_details/brief/83\" class=\"node_brief\"\x3eRead less\x3c/a\x3e \x3cbr/\x3e \x3c/span\x3e \x3c!-- description --\x3e\n" }